CAS NO. |
Products Name |
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1239875-86-5 |
SGI-7079 |
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SGI-7079 is an Axl inhibitor, significantly inhibits the proliferation of SUM149 or KPL-4 cells with an IC50 of 0.43 or 0.16 μM, respectively. |
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1645286-75-4 |
AZ6102 |
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AZ6102 is a potent TNKS1/2 inhibitor (IC50=3/1 nM) that has 100-fold selectivity against other PARP family enzymes (IC50: 0.5-3 μM) and shows 5 nM Wnt pathway inhibition in DLD-1 cells. |
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1637735-84-2 |
FIIN-3 |
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FIIN-3 is an irreversible inhibitor of FGFR1-4 with IC50s of 13, 21, 31, and 35 nM, respectively. FIIN-3strongly inhibited EGFR, with an IC50 of 204 nM. |
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118414-82-7 |
MK886 |
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MK886 is a potent 5-lipoxygenase activating protein inhibitor (FLAP) also a non-competitive inhibitor of PPAR alpha. a potent inhibitor of leukotriene (LT) biosynthesis in intact human polymorphonuclear leukocytes with IC 50 of 2.5 nM. Block the synthessis of leukotrien intact activate leukocyte. |
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864821-90-9 |
Eluxadolin |
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Eluxadoline(JNJ-27018966) is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
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1527503-11-2 |
A-366 |
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A-366 is a peptide-competitive inhibitor of G9a/GLP with an enzymatic IC50 of ~3 nM and >100-fold selectivity over other methyltransferases and other non-epigenetic targets. |
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905281-76-7 |
GDC-0879 |
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GDC-0879 is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well; no inhibition known to other protein kinases. |
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