CAS NO. |
Products Name |
313516-66-4 |
T0070907 |
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T0070907 is a potent and selective PPARγ antagonist with IC50 of 1 nM; displays > 800-fold selectivity for PPARγ over PPARα and PPARδ. |
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144217-65-2 |
YYA-021 |
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YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry, with high anti-HIV activity and low cytotoxicity. |
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312756-74-4 |
RS1 |
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RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is reported that RS-1 can be used to kill human cancer cells, and that its toxicity is modulated by both RAD51 and RAD54 translocase expression levels |
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178946-89-9 |
C-DIM12 |
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C-DIM12 is a synthetic Nurr1 activaor induces Nurr1 and DA gene expression in cell lines and primary neurons. |
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1161233-85-7 |
BTZ043 |
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BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. |
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1377239-83-2 |
PBTZ169 |
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PBTZ169 is a new drug candicate that inhibits decaprenylphosphoryl-β-d-ribose 2′-oxidase (DprE1), more efficiently than BTZ043 |
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259869-55-1 |
JWH-133 |
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JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors. |
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24144-92-1 |
TMS |
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TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). It has strong selectivity among P450 family 1 enzymes. TMS exhibits 50-fold selectivity for P450 1B1 over P4501A1 and 500-fold selectivity for P450 1B1 over P450 1A2. |
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307538-42-7 |
SMER28 |
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SMER28 is a small molecule modulator of autophagy acting via an mTOR-independent mechanism, prevented the accumulation of amyloid beta peptide. an activator of autophagy. |
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451492-95-8 |
AV412 |
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AV-412(MP-412) is a potent dual inhibitor of EGFR and ErbB2(IC50=19 nM) tyrosine kinases, including the mutant EGFR(L858R IC50=0.51 nM, T790M IC50=0.79 nM); inhibits autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. |
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755038-02-9 |
BI2536 |
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BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
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