CAS NO. |
Products Name |
1327167-19-0 |
BPR1J-097 |
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BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM. |
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1038915-60-4 |
MK4827 (Niraparib) |
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MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1. |
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844903-58-8 |
GSK163090 |
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GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively. |
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1613724-42-7 |
HTH-01-015 |
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HTH-01-015 is a potent and selective inhibitor of NUAK1 with IC50 of 100 nM, does not significantly inhibit NUAK2 (IC50 of >10 μM). |
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627536-09-8 |
SD208 |
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SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM); displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. |
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210826-40-7 |
MCC-950 |
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MCC950(CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs. |
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