CAS NO. |
Products Name |
733767-34-5 |
NSC23766 |
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NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase with IC50 of ~50 μM; does not inhibit the closely related targets, Cdc42 or RhoA. |
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1243244-14-5 |
LGK974 |
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LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM. |
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1035227-43-0 |
AZ505 |
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AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 uM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 uM); DOT1L(IC50>83.3 uM);EZH2(IC50>83.3 uM). |
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1818885-28-7 |
ARV-825 |
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ARV-825 is a BRD4 inhibitor with DC50 (50% of maximum degradation) <1nM for Burkitt's lymphoma (BL) cell lines. Affinity to BD1 and BD2 of BRD4 by ARV-825 is 90 and 28 nM, respectively. |
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376348-65-1 |
Maraviroc |
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Maraviroc (UK-427857; Selzentry; Celsentri) is a selective CCR5 antagonist (IC50= 6.4 nM); displays potent anti-HIV-1 activity. |
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521984-48-5 |
SIS3 |
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SIS3 is a potent and selective inhibitor of Smad3. a potent regulator of the human Nox4 promoter. |
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1125758-85-1 |
A804598 |
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A-804598 is a novel, competitive, and selective P2X7 receptor antagonist with IC50 of 10 nM, 9 nM and 11 nM in rat, mouse and human P2X7 receptors respectively. |
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374913-63-0 |
Madrasin |
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Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. |
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1224846-01-8 |
MK3697 |
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MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.95 nM. |
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349085-38-7 |
HC-030031 |
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HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively. |
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171500-79-1 |
Dalbavancin HCL |
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Dalbavancin(BI-397; MDL-63397) is a semisynthetic lipoglycopeptide, has potent activity against Gram-positive bacteria(MIC50=0.06 mg/L; B. anthracis). |
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