CAS NO. |
Products Name |
200626-61-5 |
ITSA-1(ITSA1) |
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ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. |
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1415716-58-3 |
TG6-10-1 |
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TG6-10-1 is an EP2 antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors. |
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873652-48-3 |
GDC0152 |
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GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively. |
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165377-44-6 |
SA-4503 |
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SA4503 2Hcl(AGY-94806 2Hcl; Cutamesine 2Hcl) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50 = 17.4 +/- 1.9 nM); 100-fold less affinity for the sigma 2 receptor. |
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1375465-91-0 |
ACY738 |
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ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold. |
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127191-97-3 |
KN62 |
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KN-62 is selective, cell-permeable inhibitor of CaM kinase II (IC50 = 0.9 μM); binds directly to the calmodulin binding site of the enzyme; potent non-competitive antagonist at the P2X7 receptor (IC50 = 15 nM). |
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328543-09-5 |
AG14361 |
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AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. |
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173529-10-7 |
hmn-176 |
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HMN-176 is a stilbene derivative which inhibits mitosis without significant effect on tubulin polymerization. |
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