CAS NO. |
Products Name |
1448428-04-3 |
Selonsertib |
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GS-4997 is a highly selective and potent once-daily oral ASK1 inhibitor that competes with ATP in the ASK1 catalytic kinase domain. |
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1346547-00-9 |
GSK583 |
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GSK583 is a highly potent and selective inhibitor of RIP2 Kinase. RIP2 kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2, leading to the production of inflammatory cytokines. |
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942398-84-7 |
Amiselimod |
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Amiselimod hydrochloride is a novel sphingosine 1-phosphate receptor-1 (S1P1) modulator, designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. |
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1445993-26-9 |
Mivebresib |
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Mivebresib, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins |
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1332708-14-1 |
PF-4840154 |
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PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively. |
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854107-55-4 |
Ponesimod |
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Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator. |
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1621862-70-1 |
CPI-1205 |
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CPI-1205 is an orally available selective inhibitor of the histone lysine methyltransferase EZH2, with potential antineoplastic activity. |
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315702-99-9 |
STF-62247 |
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STF-62247 is TGN inhibitor with IC50 of 0.625μM and 16μM in RCC4 and RCC4/VHL cells,respectively.It specifically induces autophagic cell death in cells that have lost VHL, an essential mutation in the development of RCC. |
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923262-96-8 |
SAR407899 hcl |
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SAR407899 Hcl is a potent, ATP-competitive ROCK inhibitor woth Ki value of 36 nM/41 nM for human ROCK/Rat ROCK respectively. |
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1235481-90-9 |
P7C3-A20 |
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P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-A20 exerted an antidepressant-like effect in wild-type littermates than P7C3. display increased activity and an improved toxicity profile compared to P7C3. P7C3 is a NAMPT activator. |
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179528-45-1 |
PD150606 |
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PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively). |
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