CAS NO. |
Products Name |
1380424-42-9 |
KML-29 |
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KML29 is a potent and selective MAGL inhibitor with IC50 = 5.9, 15, and 43 nM in human, mouse, and rat brain proteomes, respectively. |
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1129669-05-1 |
IM-12 |
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IM-12 is a potent GSK-3β inhibitor with IC50 of 53 nM; shows a significant activity in several biological tests which was comparable or even outplayed the effects of the known SB-216763. |
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913376-83-7 |
AMG-458 |
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AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells. |
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1422144-42-0 |
AR-13324 mesylate |
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AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes. |
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66611-37-8 |
BGP-15 |
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BGP-15 is a PARP inhibitor, that can protect against heart failure and atrial fibrillation in mice. |
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1339058-04-6 |
YL0919 |
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YL0919, a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor,the IC50 values of YL-0919 inhibiting the uptake of 5-HT into rat cerebral cortical synaptosomes and human recombinant cells were 1.78±0.34 nM and 1.93±0.18 nM respectively. |
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