CAS NO. |
Products Name |
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380917-97-5 |
Perampanel |
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Perampanel is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials. |
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441798-33-0 |
Macitentan |
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Macitentan is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM |
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1219168-18-9 |
BML-275(Dorsomorphin 2HCL) |
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Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits BMP type I receptor. |
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1493694-70-4 |
UNC2250 |
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UNC2250 is a potent and selective Mer inhibitor with IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3. |
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418805-02-4 |
PYR41 |
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PYR41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2. |
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1395084-25-9 |
MS436 |
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MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM. |
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218156-96-8 |
SRPIN 340 |
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SRPIN 340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against more than 140 other kinases.. |
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