CAS NO. |
Products Name |
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648450-29-7 |
AS-605240 |
more... |
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα, respectively |
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916141-36-1 |
TCS1102 |
more... |
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). |
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186692-46-6 |
Roscovitine |
more... |
Roscovitine (Seliciclib, CYC202) is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM. It shows little effect on CDK4/6. Phase 2. |
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405169-16-6 |
Dovitinib (TKI-258, CHIR-258) |
more... |
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2. Phase 4. |
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691852-58-1 |
Nesbuvir |
more... |
Nesbuvir, a novel selective nonstructural protein 5B (NS5B) polymerase inhibitor, act as candidate for HCV treatment. |
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252017-04-2 |
AZD7545 |
more... |
AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. |
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