CAS NO. |
Products Name |
187389-52-2 |
Z-VAD-FMK |
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Z-VAD-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks all features of apoptosis. |
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850879-09-3 |
Amuvatinib(MP470) |
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Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. |
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483367-10-8 |
Purmorphamine |
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Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM. |
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1255517-76-0 |
PF4708671 |
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PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), with a Ki of 20 nM and IC50 of 160 nM. |
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1044870-39-4 |
RVX-208 |
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RVX-208(RVX 000222) is a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo; is a BET bromodomain antagonist. |
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1439399-58-2 |
CB-839 |
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CB-839 is a potent, selective, and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC); inhibits recombinant GAC with an IC50 of <15 nM. |
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1457983-28-6 |
G-749 |
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G-749 is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants with IC50s of 0.4/0.6/3.5/7.5 nM for Wt Flt3/D835Y/MV4-11/Molm-14 respectively. |
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