CAS NO. |
Products Name |
249921-19-5 |
Anamorelin(RC1291; ONO-7643) |
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Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
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425386-60-3 |
Semagacestat (LY450139) |
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Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM. |
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116666-63-8 |
Mibefradil 2Hcl(Ro 40-5967) |
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Mibefradil 2Hcl(Ro 40-5967) is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. |
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865838-26-2 |
RX-3117 |
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RX-3117(TV-1360; Fluorocyclopentenylcytosine) is novel a cytidine analog; shows anticancer activity in several cancer cell lines, including gemcitabine-resistant variants. |
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1417162-36-7 |
RI-2 |
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RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells. |
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1421373-62-7 |
Mutant EGFR inhibitor |
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Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor(L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant). |
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