CAS NO. |
Products Name |
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405554-55-4 |
SB-590885 |
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SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases. |
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896720-20-0 |
VX-11e |
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VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-RegulatedKinase). Antitumor agents |
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755038-65-4 |
Volasertib(BI6727) |
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Volasertib (BI 6727) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. |
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667463-85-6 |
BIO-acetoxime |
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BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. |
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1146963-51-0 |
J147 |
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J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF). |
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356559-20-1 |
SB525334 |
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SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6. |
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1598383-40-4 |
EPZ011989 |
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EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase. |
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