CAS NO. |
Products Name |
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714971-09-2 |
AC480 (BMS-599626) |
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AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. |
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940310-85-0 |
NVP-BHG712 |
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NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively. |
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1276553-09-3 |
PF-4989216 |
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PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively. |
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164178-33-0 |
AM630 |
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AM630 CB2 antagonist, Ki 31.2 nM, 150 times times higher than for the CB1 receptor, inhibitory or more. |
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