CAS NO. |
Products Name |
|
|
1431326-61-2 |
ORY-1001 (RG-6016) |
more... |
ORY-1001 (RG-6016) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. |
|
869901-69-9 |
MK-2048 |
more... |
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively. |
|
|
138489-18-6 |
Ro 31-8220 |
more... |
Ro 31-8220 is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3β and S6K1. |
|
62996-74-1 |
Staurosporine |
more... |
Staurosporine is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. |
|
|
1180676-32-7 |
PS48 |
more... |
PDK1 PS48 is a small molecule agonists and Kd value is 10.3uM, the specificity of PDK1 PIF-binding of pocket, different from the ATP binding site. |
|
|
|
HO-3867 |
more... |
HO-3867, an analog of curcumin, is a selective STAT3 inhibitor. |
|
|