CAS NO. |
Products Name |
|
1000669-72-6 |
KW2449 |
more... |
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. |
|
1542705-92-9 |
CB5083 |
more... |
CB-5083 is a potent, ATP-competitive, D2-selective, and orally bioavailable p97 inhibitor with IC50 of 11nM. |
|
186611-52-9 |
SU-5607 |
more... |
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM. |
|
|
714971-09-2 |
BMS599626 |
more... |
AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. |
|
903576-44-3 |
Ciproxidine |
more... |
Pitolisant Hcl(BF2.649;Ciproxidine ) is a novel, potent, and selective nonimidazole inverse agonist at the recombinant human H3 receptor (Ki=0.16 nM). |
|
|
|
869901-69-9 |
MK2048 |
more... |
MK-2048 is a potent inhibitor of integrase and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively. |
|
1357470-29-1 |
ON123300 |
more... |
ON123300 is a potent inhibitor of CDK4, with an IC50 of 3.8 nM, with little inhibitory activity against CDKs 1,2,5 and 8. |
|
1197953-54-0 |
Brigatinib |
more... |
Brigatinib is a highly potent and selective investigational ALK inhibitor with mean IC50 value < 100 nM in Ba/F3 cells. |
|