CAS NO. |
Products Name |
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210826-40-7 |
MCC-950 |
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MCC950(CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs. |
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1564286-55-0 |
CWHM12 |
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CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
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935273-79-3 |
MK4101 |
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MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway, highly active against Medulloblastoma and Basal Cell Carcinoma. |
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1235560-28-7 |
ABT639 |
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ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 blocks recombinant human T-type (Cav3.2) Ca2+ channels in a voltage-dependent fashion (IC50 = 2 μM) and attenuates LVA currents in rat DRG neurons (IC50 = 8 μM). |
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728865-23-4 |
chir-090 |
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CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. |
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1384426-12-3 |
NT157 |
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NT157is a selective inhibitor of IRS-1/2, IC50 values at sub-micromolar doses (ranging from 0.3 to 0.8 μM) . |
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117570-53-3 |
DMXAA |
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DMXAA is a competitive inhibitor of the enzyme DT-diaphorase (NAD(P)H:Quinone oxidoreductase EC 1.6.99.2) with respect to NADH, with Ki values of 20 μM. |
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139504-50-0 |
DM1 |
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Mertansine is a tubulin inhibitor,inhibits the assemblyof microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). |
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444805-28-1 |
Brincidofovir(CMX001) |
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CMX001 (Brincidofovir; HDP-CDV) was developed as an orally active, lipophilic form of cidofovir (CDV); has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses. |
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50-76-0 |
Dactinomycin D |
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Dactinomycin D(Actinomycin D; Oncostatin K) is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. |
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166663-25-8 |
Anidulafungin |
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Anidulafungin (LY303366) is a semisynthetic echinocandin used as an antifungal drug. Anidulafungin acts by inhibiting (1,3)-beta-D-glucan synthesis in the fungal cell wall. |
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