CAS NO. |
Products Name |
1420071-30-2 |
Bioymifi |
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Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. |
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1015474-32-4 |
CC122 |
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CC-122 is a novel agent for DLBCL with antitumor and immunomodulatory activity.CC-122 binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. |
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920509-32-6 |
MGL-3196 |
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MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM. |
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947914-18-3 |
ML365 |
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ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3) with IC50 of 4 nM(thallium influx fluorescent assay) and 16 nM(automated electrophysiology assay). |
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1237744-13-6 |
QNZ46 |
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QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively). |
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252025-52-8 |
AF-2364 |
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Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway. |
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478336-92-4 |
ISO-1 |
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ISO-1 is an inhibitor of MIF d-dopachrome tautomerase activity with an IC50 of about 7 uM. |
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501437-28-1 |
BI-D1870 |
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BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B. BI-D1870 also has a Kd value of 3.5 uM for BRD4. |
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1462249-75-7 |
PFK-158 |
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PFK-158 is a potent and selective inhibitor of PFKFB3 that is currently being investigated in a phase I study in patients with advanced solid malignancies. |
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1799753-84-6 |
BAY-876 |
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BAY-876 is the first highly selective GLUT1 inhibitor with IC50 of 0.002 uM. show good metabolic stability in vitro and high oral bioavailability in vivo. |
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