CAS NO. |
Products Name |
81624-55-7 |
NSC348884 |
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NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines. |
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1404437-62-2 |
ML281 |
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ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA. |
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1118567-05-7 |
EGT1442 |
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Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. |
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939981-39-2 |
RG7112 |
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RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2. |
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649735-46-6 |
Brivanib(BMS540215) |
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Brivanib(BMS540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. |
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586379-66-0 |
PH-797804 |
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PH-797804 is an ATP-competitive, readily reversible inhibitor of the α isoform of human p38 MAP kinase, exhibiting a Ki = 5.8 nM. |
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1228013-30-6 |
CC-223 |
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CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM). |
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900185-01-5 |
PIK-293 |
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PIK-293 is a $literal inhibitor, the most effective roles in PI3K Delta, IC50 0.24, for PI3K alpha / beta / gamma effect low of 500,100 and 50 times times respectively. |
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